Funding for this research was provided by:
Cancer Research UK (C5255/A23755)
Wellcome Trust (209397/Z/17/Z)
Received: 21 February 2020
Accepted: 5 June 2020
First Online: 19 August 2020
Ethics approval and consent to participate
: All animal protocols were approved by the University of Oxford Clinical Medicine Animal Welfare Ethics Review Board and conducted under animal project licences (PPL) P4B738A3B and P8484EDAE.
: The authors declare that they have no competing interests.