Received: 25 March 2019
Accepted: 4 September 2019
First Online: 3 October 2019
Ethics approval and consent to participate
: Ethical approval was obtained at each centre, when applicable. Consent was not required.
: Not applicable.
: Eisen reports other financial interests with Astrazeneca and grants from Pfizer, Bayer and Astrazeneca, outside the submitted work. All other authors declare that they have no competing interests.