Funding for this research was provided by:
Wellcome Trust (206470/Z/17/Z)
British Heart Foundation (PG/19/54/34511)
Received: 10 March 2020
Accepted: 29 June 2020
First Online: 24 August 2020
Ethics approval and consent to participate
: Ethical approval was not required under the National Health Service (NHS) research governance arrangements. The National Institute for Cardiovascular Outcomes Research (NICOR) which includes the Myocardial Ischaemia National Audit Project (MINAP) database (ref: NIGB: ECC 1-06 (d)/2011) has support under section 251 of NHS Act 2006 to use patient information for medical research without consent.
: Not applicable.
: MH has received research grants from the Wellcome Trust for the submitted work; CPG has received personal fees and non-financial support from AstraZeneca; research grants and personal fees from BMS; research grants, personal fees and non-financial support from Bayer; personal fees and non-financial support from Daiichy Sankyo; and personal fees and non-financial support from Vifor Pharma, outside the submitted work. CGW reports research grants from Bristol-Myer-Squibb, outside the submitted work; no other relationships or activities that could appear to have influenced the submitted work.