Funding for this research was provided by:
German Research Foundation (STR 1095/4-2 (to P.S.), MU 1373/9-1 (to S.M.) and BR 4182/3 1)
Else Kröner-Fresenius-Stiftung (Else Kröner Excellence Fellowship)
German Liver Foundation (DLS)
Medical faculty at RWTH Aachen University (START program)
Faculty of Medicine at the RWTH Aachen University (Interdisciplinary Center for Clinical Research (IZKF))
Received: 18 February 2020
Accepted: 16 September 2020
First Online: 12 November 2020
Ethics approval and consent to participate
: For all cohorts, ethics approval and informed consent to participate in the study is available (cohort i: institutional review board of Aachen University, cohort ii: Ethikkommission der Medizinischen Universität Wien, cohort iii: Comité d’Ethique d’Aulnay-Sous-Bois, cohort iv: Ethikkommission des Universitätsklinikums Jena). All patients provided written informed consent, if the requirement of informed consent was not waived.
: Not applicable.
: All authors declare no support from any organization other than the below mentioned ones for the submitted work, no financial relationships with any organizations that might have an interest in the submitted work in the previous 3 years, and no other relationships or activities that could appear to have influenced the submitted work. Hence, all authors declare themselves to be independent from funders with respect to this manuscript.