Funding for this research was provided by:
NIHR Oxford Biomedical Research Centre (BRC-1215-20005, MR/L023784/2)
Medical Research Council (MC-PC-17215)
Engineering and Physical Sciences Research Council (EP/N026977/1)
National Institute for Health Research (RP-2017-08-ST2-006)
Received: 11 August 2021
Accepted: 11 January 2022
First Online: 1 February 2022
: We assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008. All procedures involving human subjects/patients were approved by the local CRIS oversight committee and are covered by approval for the CRIS database granted by the Oxfordshire and Southern Health Research Ethics Committee. Individual patient consent is not required for this use of anonymised, routine data.
: Individual patient consent is not required for this use of anonymised, routine data.
: Ivan Koychev is a paid medical advisor for Cognetivity, Mantrah and Sharp Therapeutics companies which specialise in developing digital solutions for monitoring cognition or supporting independence in patients. Andrea Cipriani has received research and consultancy fees from INCiPiT (Italian Network for Paediatric Trials), CARIPLO Foundation and Angelini Pharma, outside the submitted work. Alejo Nevado-Holgado works as a consultant in Akrivia Health (ExternalRef removed) and has obtained funding from Johnson & Johnson, Ono Pharma and GSK. None of those funds is involved in this publication. The other authors declare no conflicts of interest.