Funding for this research was provided by:
National Key Research and Development Project of China (2017YEFD110300, 2019YFC1315904)
National Key Research and Development Program of China (2019YFC1315800)
National High Level Hospital Clinical Research Funding (2022-PUMCH-B-061)
CAMS Innovation Fund for Medical Sciences (2021-I2M-1-002)
234 Discipline Climbing Plan Project of the First Affiliated Hospital of Naval Military Medical University (2019YXK033)
Received: 19 July 2022
Accepted: 1 November 2022
First Online: 25 November 2022
: This project was approved by Peking Union Medical College Hospital (PUMHC) Ethics Committee (No. JS-1490) and Changhai Hospital, Navy Medical University (CHNMU) (No. CHEC2020-113). All patients and healthy control volunteers have given informed consent.
: Not applicable.
: The following authors are employees of Singlera Genomics (Shanghai) Ltd.: Zhixi Su, Qiye He, Chengcheng Ma, Rui Liu. The other authors declare that they have no competing interests.