Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (DFG PO 681/8-1)
Received: 19 December 2018
Accepted: 10 January 2020
First Online: 20 January 2020
Ethics approval and consent to participate
: Animal experiments were conducted in accordance with the German Animal Welfare Law and all experiments were approved by the local authorities (Niedersächsisches Landesamt für Verbraucherschutz und Lebensmittelsicherheit (LAVES), Oldenburg, Germany, permission numbers: 33.9–42502-05-12A241, 33.19–42502-05-16A044).In addition, brain tissues from dogs unrelated to the animal experiments were used. Brain tissues originate from the archive of the Department of Pathology of the University of Veterinary Medicine in Hanover, Germany. The authors confirm that none of these dogs was sacrificed for the purpose of this study. The use of brain tissue from these dogs is no animal experiment since all of these animals were dead at the time of submission for necropsy in order to investigate the causes of death and disease. All dog owners provided written consent for the dogs’ tissues to be collected and used for research purposes.
: Not applicable.
: The authors declare that they have no competing interests.