Funding for this research was provided by:
National Science Foundation (1456634, 1622840)
Received: 17 February 2017
Accepted: 2 October 2017
First Online: 6 October 2017
Ethics approval and consent to participate
: The samples used in this study were de-identified DNA samples from CHLA patients; 33 of the samples were used for validation of our Clinical Exome Sequencing (CES) test. They are stored at the CHLA Pediatric Research Biorepository, which has granted the institutional waiver of consent for research purposes. Furthermore, the patients have granted us the permission to share their anonymized data using the patient consent form.
: Patients have granted us the permission to share their anonymized data using the patient consent form.
: The authors declare that they have no competing interests.
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