Funding for this research was provided by:
Wellcome Trust (105104/Z/14/)
Prostate Cancer UK (PG12-49)
Cancer Research UK (A13239)
European Society of Medical Oncology
Medical Research Council
FP7 People: Marie-Curie Actions
Received: 21 November 2018
Accepted: 15 July 2019
First Online: 2 August 2019
Ethics approval and consent to participate
: All samples were collected in studies with institutional regulatory board approval and conducted in accordance with the Declaration of Helsinki and the Good Clinical Practice guidelines of the International Conference of Harmonization. The protocols were approved by: The Royal Marsden Research Ethics Committee at the Royal Marsden, London, UK (REC number 04/Q0801/6), Comitato Etico IRST IRCCS AVR at the Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy (REC number 2192/2013) and The Peter MacCallum Cancer Centre Ethics Committee [EC00235] at The Peter MacCallum Cancer Centre, Melbourne, Australia (REC number 15/98). Written informed consent was obtained from all patients.
: Patients have consented that next-generation sequencing data with no personal identifiers can be used for publication in an anonymized format.
: The authors declare that they have no competing interests.