Funding for this research was provided by:
National Heart, Lung, and Blood Institute (HL054457, HL100185, HL119443, HL133221)
National Institute of Neurological Disorders and Stroke (NS041558)
Received: 8 October 2018
Accepted: 11 September 2019
First Online: 22 October 2019
Ethics approval and consent to participate
: Written informed consent was obtained from all participants, and Institutional Review Boards at the University of Michigan, University of Mississippi Medical Center, and Mayo Clinic approved this study.
: Not applicable.
: The authors declare that they have no competing interests.