Funding for this research was provided by:
Dongguan Social Development Project (201950715007158)
Received: 1 August 2019
Accepted: 30 April 2020
First Online: 7 May 2020
Ethics approval and consent to participate
: Written informed consent to participate in the genetic testing and this study was obtained from the patients’ families, including the patients, the patient’s mothers, the patient’s uncle in Family 1, and the maternal grandparents in Family 3. This study was approved by the Committee on Ethics of the Dongguan Maternal and Child Health Care Hospital and was performed in accordance with the Declaration of Helsinki.
: Written informed consent for publication of clinical and genetic data was obtained from all participants. The parents /legal guardian of the children (under the age of 18) has signed written informed consent for publication of clinical and genetic data.
: The authors declare that they have no competing interests.