Funding for this research was provided by:
Russian Science Foundation (15-14-00043)
Text and Data Mining valid from 2018-04-09
Received: 13 December 2017
Accepted: 27 March 2018
First Online: 9 April 2018
: The study was carried out in strict accordance with the Russian Guidelines for the Care and Use of Laboratory Animals (1977). The protocol was approved by the Committee for Ethics of Animal Experimentation, Research Institute of Influenza. All efforts were made to minimize animal suffering. Mice were housed in cages provisioned with water and standard food, and they were monitored daily for health and condition. More than 25% body weight loss was used as a criterion for early euthanasia; animals were euthanized by CO2inhalation for 5 min. After final monitoring (day 14 post challenge), all of the surviving mice were humanely euthanized (as above).
: Not applicable
: The authors declare that they have no competing interests.
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