Funding for this research was provided by:
Ministry of Science and Technology (103-2314-B-039-035-MY3, 105-2628-B-039-008-MY3)
Received: 20 July 2019
Accepted: 9 January 2020
First Online: 15 January 2020
Ethics approval and consent to participate
: The SSc patients’ sera were obtained from Dr. Lan and this study was approved by the Institutional Review Board (IRB) of China Medical University Hospital, Taichung, Taiwan (cmuh105-rec3–005). The usage of all clinical specimens was anonymous.All animal studies were according to protocols approved by Laboratory Animal Committee of China medical University (Approval No.2018–226).
: Not applicable.
: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.