Wilson, Ava C.
Kumar, Preeti L.
Lee, Sool
Parker, Margaret M.
Arora, Itika
Morrow, Jarrett D.
Wouters, Emiel F. M.
Casaburi, Richard
Rennard, Stephen I.
Lomas, David A.
Agusti, Alvar
Tal-Singer, Ruth
Dransfield, Mark T.
Wells, J. Michael
Bhatt, Surya P.
Washko, George
Thannickal, Victor J.
Tiwari, Hemant K.
Hersh, Craig P.
Castaldi, Peter J.
Silverman, Edwin K.
McDonald, Merry-Lynn N.
Funding for this research was provided by:
National Institutes of Health (R00HL121087, R01HL130512, R01HL125583, U01 HL089856, U01 HL089897)
GlaxoSmithKline (ECLIPSE)
COPD Foundation
Article History
Received: 15 January 2020
Accepted: 11 March 2020
First Online: 1 May 2020
Ethics approval and consent to participate
: Institutional Review Board approval for all analyses was obtained from the University of Alabama at Birmingham and have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. All subjects included in this analysis provided written informed consent prior to their inclusion in the respective studies mentioned below.
: Not Applicable.
: ACW, PLK, SL, MMP, IA, HKT, VJT, GW, MW, AA, SR, and RC report no conflicts of interest. JM reports grants from NIH NHLBI, during the conduct of the study. EW reports board membership for Nycomed and Boehringer, grants from AstraZeneca and GlaxoSmithKline, and payment for lectures including service on speakers’ bureaus from GlaxoSmithKline, Novartis, and Chiesi. DL has received grant support, honoraria and consultancy fees from GSK. SPB is supported by NIH grant K23HL133438. He has served on advisory boards for Sunovion and GlaxoSmithKline. CH reports grants from National Institutes of Health, during the conduct of the study; personal fees from AstraZeneca, personal fees from Concert Pharmaceuticals, personal fees from 23andMe, grants from Novartis, grants from Boehringer-Ingelheim, outside the submitted work. EKS received grants and travel support from GlaxoSmithKline within the past three years. MLM reports grants from NIH, other from Parker B. Francis Foundation, during the conduct of the study; personal fees from Pfizer, outside the submitted work. RTS reports personal fees from GlaxoSmithKline, during the conduct of the study. MTD reports grants from NIH, American Lung Association, Department of Defense, and the Department of Veterans Affairs; personal fees from AstraZeneca, Boehringer Ingelheim, PneumRx/BTG, Mereo, Quark Pharmaceuticals and GSK, and contracted clinical trial support from Boehringer Ingelheim, Novartis, AstraZeneca, Yungjin, PneumRx/BTG, Pulmonx, Boston Scientific, Gala, Nuvaira, and GSK. PJC has received research support and consulting fees from GSK and Novartis. JMW reports grants from NIH/NHLBI, during the conduct of the study; grants from NIH/NCATS, grants from Bayer, grants and other from GSK, other from Boehringer Ingelheim, grants and other from Mereo BioPharma, other from PRA, outside the submitted work; .