Rabe, Klaus F.
Halpin, David M. G.
Han, MeiLan K.
Miravitlles, Marc
Singh, Dave
Grönke, Lars
Voß, Florian
Martinez, Fernando J.
Funding for this research was provided by:
Boehringer Ingelheim (N/A)
Article History
Received: 7 November 2019
Accepted: 21 June 2020
First Online: 9 July 2020
Ethics approval and consent to participate
: All studies included in this analysis were performed in accordance with the provisions of the Declaration of Helsinki (1996 version), in accordance with the International Conference on Harmonization Tripartite Guideline for Good Clinical Practice, and in accordance with applicable regulatory requirements and Boehringer Ingelheim Standard Operating Procedures. All patients provided written informed consent. This article does not report individual patient data; all data presented here are anonymised. The clinical trial protocols and the informed consent and patient information forms were reviewed and received approval/favourable opinion from a constituted local Institutional Review Board or an Independent Ethics Committee at each centre prior to the start of the study.
: K.F.R. reports personal fees from Boehringer Ingelheim, AstraZeneca, Novartis and Chiesi, and grants from Boehringer Ingelheim, AstraZeneca and Takeda, outside the submitted work. D.M.G.H. reports personal fees from AstraZeneca, Chiesi and Pfizer, and grants and personal fees from Boehringer Ingelheim, GlaxoSmithKline and Novartis, outside the submitted work.M.M. reports speaker fees from AstraZeneca, Boehringer Ingelheim, Chiesi, Cipla, Menarini, Rovi, Bial, Zambon, CSL Behring, Grifols and Novartis, and consulting fees from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Bial, Gebro Pharma, CSL Behring, Laboratorios Esteve, Ferrer, Mereo Biopharma, Verona Pharma, TEVA, pH Pharma, Novartis and Grifols and research grants from GlaxoSmithKline and Grifols.M.K.H. reports consultancy fees from Boehringer Ingelheim, GlaxoSmithKline, AstraZeneca and Mylan, speaker fees from Boehringer Ingelheim, and research support from Novartis Sunovion, outside the submitted work. F.J.M. reports grants from NHLBI during the conduct of the study, grants from the National Institutes of Health, personal fees from Continuing Education, Forest Laboratories, GlaxoSmithKline, Nycomed/Takeda, AstraZeneca, Boehringer Ingelheim, Bellerophon Therapeutics (formerly Ikaria), Genentech, Novartis, Pearl, Roche, Sunovion, Theravance, CME Incite, the Annenberg Center for Health Sciences at Eisenhower, Integritas, InThought, the National Association for Continuing Education, Paradigm Medical Communications, LLC, PeerVoice, UpToDate, Haymarket Communications, the Western Society of Allergy and Immunology, ProterixBio (formerly Bioscale), Unity Biotechnology, Concert Pharmaceuticals, Lucid, Methodist Hospital, Columbia University, Prime Healthcare Ltd., WebMD, PeerView Network, the California Society of Allergy and Immunology, Chiesi and the Puerto Rico Thoracic Society, and advisory board participation for Janssen, outside the submitted work. D.S. reports personal fees from Apellis, Cipla, Genentech, Peptinnovate and Skyepharma, and grants and personal fees from AstraZeneca, Boehringer Ingelheim, Chiesi, Glenmark, Merck, Mundipharma, Novartis, Pfizer, Pulmatrix, Teva, Theravance and Verona, outside the submitted work. L.G. was an employee of Boehringer Ingelheim at the time of the study and is now employed by CSL Behring. F.V. is an employee of Boehringer Ingelheim.