Funding for this research was provided by:
Chiesi Farmaceutici (N/A)
Text and Data Mining valid from 2020-03-20
Received: 17 October 2019
Accepted: 27 February 2020
First Online: 20 March 2020
Ethics approval and consent to participate
: The study was approved by independent ethics committees for each institution (see the supplement for details). All patients provided written informed consent prior to study start.
: Not applicable.
: MG, MB, SV, GL, AE, MAN and SP are employees of Chiesi, the sponsor of this study.GLJ and EKA are employees of the Almac group; Almac received funding from Chiesi as part of a consultation fee for the work reported in this manuscript.BC and BL have nothing to disclose.OK’s institution received fees from Chiesi for conducting this study as a participating site. He reports personal fees as speaker or Advisory Board member from AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Sanofi and Novartis.KMB declares that no personal payments were received from any pharmaceutical entity in the past 5 yrs. He is a full time employee of insaf Respiratory Research Institute. The institution has received compensation for services on advisory boards or consulting for Ablynx, Almirall, AstraZeneca, Berlin Chemie, Boehringer, Chiesi, Cytos, Mundipharma, Novartis, Pohl Boskamp, Zentiva. The institution has received compensation for speaker activities in scientific meetings supported by Almirall, AstraZeneca, Berlin Chemie, Boehringer, Cytos, ERT, GSK, Novartis, Pfizer, Pohl Boskamp, Takeda. The institution has received compensation for design and performance of clinical trials from Almirall, Altana/Nycomed, AstraZeneca, Boehringer, Cytos, GSK, Infinity, Medapharma, MSD, Mundipharma, Novartis, Parexel, Pearl Therapeutics, Pfizer, Revotar, Teva, Sterna, and Zentiva.HW reports personal fees from Chiesi during the conduct of the study. Outside the submitted work, Dr. Watz reports personal fees from Bayer, personal fees from GSK, personal fees from Boehringer Ingelheim, personal fees from Novartis, personal fees from AstraZeneca, personal fees from BerlinChemie, and personal fees from Roche.DS received personal fees from Chiesi during the conduct of this study. Outside the submitted work, he reports grants and personal fees from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Glenmark, Menarini, Mundipharma, Novartis, Pfizer, Pulmatrix, Therevance, and Verona, and personal fees from Cipla, Genentech and Peptinnovate.