Funding for this research was provided by:
Received: 12 December 2020
Accepted: 11 February 2021
First Online: 19 February 2021
Ethics approval and consent to participate
: Subjects who participated in the AIRFLOW 1 clinical trial have given their informed consent to participate in this trial. The study protocol was approved by each research institutions committee on human research, see Ref. [CitationRef removed].
: The authors do not plan to share individual deidentified participant data.
: The AIRFLOW-1 clinical trial was funded by Nuvaira, Inc., Minneapolis, MN, USA. PLS and DJS are investigators and advisors to Nuvaira, Inc. ADP and MM are employees of Nuvaira, Inc. CP, VN, WJ, TP, RK, GD, JLG, JEH, BD, AM, AV have nothing to disclose in relation to this work.