Funding for this research was provided by:
the National Basic Research Program of China (81800317)
the Union Program of the Key Scientific and Technological Project of Henan Province (2018020008)
Received: 27 December 2019
Accepted: 6 February 2020
First Online: 19 February 2020
Ethics approval and consent to participate
: The study protocol followed the Declaration of Helsinki and was approved by the Ethics Committees of participating centers. All participants signed written informed consent.
: All authors consent this manuscript for publication.
: The authors declare that they have no competing interests.