Funding for this research was provided by:
Natural Science Foundation of Beijing Municipality (7181008)
The National Key Research and Development Program of China (2016YFC1301300, 2016YFC1301301)
CAMS Innovation Fund for Medical Sciences (2016-I2M-1-002)
Young and middle-aged talents in the XPCC Science and Technology Project (2020CB012)
Received: 20 September 2020
Accepted: 9 December 2020
First Online: 11 January 2021
Ethics approval and consent to participate
: The study was conducted in accordance with the Declaration of Helsinki and was approved by the local ethics committee of the Fuwai hospital’s Research Ethics Committee. The Institutional Review Board approved the study protocol and all of the patients provided written informed consent.
: the manuscript was approved by all authors for publication.
: All authors state that they have no competing interests.