Stevens, Susanna R.
Segar, Matthew W.
Pandey, Ambarish
Lokhnygina, Yuliya
Green, Jennifer B.
McGuire, Darren K.
Standl, Eberhard
Peterson, Eric D.
Holman, Rury R.
Article History
Received: 4 March 2022
Accepted: 14 August 2022
First Online: 27 August 2022
Declarations
:
: The trial was designed and overseen by a steering committee, and an independent data and safety monitoring committee performed regular safety surveillance. All patients provided written informed consent. Institutional review board approval was required at all participating institutions.
: Not applicable.
: MWS has received personal fees from Merck & Co. YL has received grants from Merck, Janssen Research & Development, AstraZeneca, GlaxoSmithKline, and Bayer HealthCare AG. JBG has received grants from AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline and Sanofi, and personal fees from AstraZeneca, Merck, Boehringer-Ingelheim, Sanofi/Regeneron, and NovoNordisk. DKM has received honoraria for clinical trial leadership for Lilly US, AstraZeneca, Sanofi, Janssen, Boehringer Ingelheim, Merck & Co, Novo Nordisk, Lexicon, Eisai, GlaxoSmithKline, CSL Behring and Esperion, and for consultancy for Afimmune, AstraZeneca, Sanofi, Lilly US, Boehringer Ingelheim, Merck & Co, Pfizer, Novo Nordisk, Applied Therapeutics, and Metavant. ES reports personal fees from the Oxford Diabetes Trials Unit, AstraZeneca, Bayer, Berlin Chemie, Boehringer Ingelheim, Menarini, Merck Serono, Excemed, Novartis, NovoNordisk, and Sanofi. EDP has received grant support from Janssen, Merck, Sanofi, AstraZeneca, Genentech, and Amgen; and has had consulting associations with Bayer, Merck, Sanofi, and Janssen. RRH reports research support from AstraZeneca, Bayer and Merck Sharp & Dohme, and personal fees from Anji Pharmacueticals, Bayer, Novartis and Novo Nordisk. All other authors report no disclosures or conflicts of interest.