Funding for this research was provided by:
National Institute of Allergy and Infectious Diseases (R21AI119771)
Received: 27 March 2019
Accepted: 23 August 2019
First Online: 29 August 2019
Ethics approval and consent to participate
: Before the trial began, the experimental protocol was reviewed and approved by Institutional Animal Care and Use Committees from both the University of North Dakota and the University of Notre Dame. Principal Investigators received training certification from the American Association for Laboratory Animal Science on the experimental use of livestock in research. Signed informed consent was obtained from the livestock owner prior to beginning the trial and included an explanation of the aim, risks and benefits of the trial. The livestock owner was encouraged to ask questions and was free to withdraw his animals at anytime during the trial if he felt so inclined. The ivermectin product, Labimectin<sup>®</sup>, was registered in Belize for use in beef cattle but the fipronil product, Ectonil<sup>®</sup>, was not. Before the trial began, Principal Investigators obtained a Certificate of Registration for the experimental use of Ectonil<sup>®</sup> for this study from the Veterinary Drug and Animal Feed Registrar of the Belize Agricultural Health Authority.
: Not applicable.
: The authors declare that they have no competing interests.