Funding for this research was provided by:
National Natural Science Foundation of China (81871951, 81772614)
Received: 28 March 2019
Accepted: 19 June 2019
First Online: 24 June 2019
Ethics approval and consent to participate
: The clinical CRC specimens were conducted with permission from the Institutional Research Ethics Committee of Sun Yat-sen University Cancer Center, China. All animal experiments were performed in accordance with a protocol approved by the ethics committee of the Institutional Animal Care of Sun Yat-sen University Cancer Center, China.
: The content of this manuscript has not been previously published and is not under consideration for publication elsewhere.
: The authors declare that they have no competing interests.