Funding for this research was provided by:
Key Technologies Research and Development Program (2016YFA0501800)
National Natural Science Foundation of China (81572256, 81772766, 81871864)
Text and Data Mining valid from 2019-11-29
Received: 18 July 2019
Accepted: 21 November 2019
First Online: 29 November 2019
Ethics approval and consent to participate
: This study was reviewed and approved by the Ethnics Committees of Sir Run Run Shaw Hospital of Zhejiang University School of Medicine (Hangzhou, China). The study was conducted in accordance with the International Ethical Guidelines for Biomedical Research Involving Human Subjects. All subjects provided informed consent to participate in the study. All mouse studies were conducted according to protocols approved by the Zhejiang University Institutional Animal Care and Use Committee. All efforts were made to minimize animal suffering.
: All authors have agreed to publish this manuscript.
: The authors declare that they have no competing interests.