Funding for this research was provided by:
Received: 31 October 2019
Accepted: 26 June 2020
First Online: 6 July 2020
Ethics approval and consent to participate
: The study protocols were approved by the institution’s Research Ethics Committee (at the Grigore T. Popa University of Medicine and Pharmacy, Iași, Romania) (registration no. 25812/11.XI.2014).All animal procedures were performed in accordance with European Union legislation (EU Directive 2010/63/EU for animal experiments) on the care and use of animals for scientific purposes and in accordance with the Helsinki Declaration recommendations.As this manuscript presents the results of an experimental study on laboratory animals (rats) and not the results of a clinical study, the subject consent requirement does not apply.
: All authors of this manuscript have read and approved the final version submitted.The representatives of the Institute (the Grigore T. Popa University of Medicine and Pharmacy, Iași, Romania) are fully aware of this submission.
: The authors of this manuscript declare that there is no competing interest or conflict of interest regarding this manuscript and the experimental work involved.