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The in vitro Mycobacterium bovis BCG Moreau infection of human monocytes that induces Caspase-1 expression, release and dependent cell death is mostly reliant upon cell integrity

Crossref DOI link: https://doi.org/10.1186/s12950-019-0223-1

Published Online: 2019-07-15

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Antas, Paulo R. Z. http://orcid.org/0000-0002-6168-9185
Ponte, Carlos G. G.

Almeida, Matheus R.

Albuquerque, Lawrence H. P.

Sousa-Vasconcelos, Periela S.

Pedro, Thaíze

Gomes, Natália L. S.

Moreira, Otacílio C.

Silva, Fernanda C.

Castello-Branco, Luíz R. R.

Pinho, Rosa T.
Funding

Funding for this research was provided by:

Fundação Oswaldo Cruz (NA)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (PQ-2, INCT-TB, NA)

FAPERJ (JCNE)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (NA, NA)

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (NA)
License Information

Text and Data Mining valid from 2019-07-15

Version of Record valid from 2019-07-15
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Article History

Received: 10 January 2019

Accepted: 2 July 2019

First Online: 15 July 2019

Ethics approval and consent to participate

: The HUGG-UNIRIO (protocol # 59117015.0.0000.5258) and the IOC-Fiocruz (protocol # 35775014.0.0000.5248) institutional review boards approved the study procedures. All study participants (healthy adults, mothers of neonates, public health authorities, and the children’s parents or guardians) voluntarily provided their written informed consent.

: Not applicable.

: The authors declare that they have no competing interests.

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