Funding for this research was provided by:
National Institutes of Health (U01DA021525, U01DA0251525, U01DA038886)
Canadian Institutes of Health Research (MSH-141971, SMN-139148)
Received: 15 June 2020
Accepted: 7 December 2020
First Online: 14 December 2020
Ethics approval and consent to participate
: All participants provided informed consent for study participation. The cohort studies have received approvals from the University of British Columbia/Providence Health Care Research Ethics Board.
: Not applicable.
: The authors declare that they have no competing interests.