Funding for this research was provided by:
Metchley Park Medical Society (NA)
Received: 8 November 2019
Accepted: 5 June 2020
First Online: 10 June 2020
Ethics approval and consent to participate
: The study was approved by the National Research Ethics Service (NRES), West Midlands, Birmingham (Reference number: 16/WM/0198) and by the University Hospitals Birmingham (UHB) NHS Trust Research and Development Department (Reference number: RRK5790).
: All participants provided written informed consent.
: MC has received personal fees from Astellas, Takeda, Glaukos and Merck outside the submitted work and grants from the NIHR, Health Data Research UK and Innovate UK, part of UK Research and Innovation. OLA reports personal fees from Gilead Sciences Ltd. DK is supported by the NIHR postdoctoral fellowship scheme (PDF-2016-09-009). DK reports grants from Macmillan Cancer Support, Innovate UK, the National Institute for Health Research (NIHR), NIHR Birmingham Biomedical Research Centre and NIHR Surgical Reconstruction and Microbiology Research Centre (SRMRC) at the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust and personal fees from Merck outside the submitted work.