Received: 9 May 2019
Accepted: 16 December 2020
First Online: 12 June 2021
Ethics approval and consent to participate
: The parallel studies (OpiMA1-NZ and Japan) were approved by the Clinical Research Ethics Committees of Otago University (NZ) and Asai Hifuka Institutional Review Board (Japan).
: Not applicable.
: RT was the founder of m-PowerD Ltd (formed to hold the IP for Psynary) but no longer has ownership nor any shares nor financial links with the company. LAK is the founder of International Medical KK. Both RT and LAK are creators of Psynary. RP—Use of computer software at no cost for research – provided by SBT-pro, Received support for travel to educational meetings from Servier and Lundbeck.