Engellau, Jacob http://orcid.org/0000-0003-4424-5985
Seeger, Leanne
Grimer, Robert
Henshaw, Robert
Gelderblom, Hans
Choy, Edwin
Chawla, Sant
Reichardt, Peter
O’Neal, Michael
Feng, Amy
Jacobs, Ira
Roberts, Zachary J.
Braun, Ada
Bach, Bruce A.
Funding for this research was provided by:
Amgen
Article History
Received: 7 May 2018
Accepted: 21 August 2018
First Online: 19 September 2018
Ethics approval and consent to participate
: The study was approved by the institutional review board or ethics committee for each site, and all patients provided written informed consent.
: By giving written informed consent, all patients gave their approval for publication of the results of the study. There are no individually identifiable patient-level data.
: JE has received fees for lectures on GCTB and participation on scientific advisory boards regarding denosumab for Amgen Inc. He is a member of the board of directors for Genovis Inc. LS has served as consulting radiologist for Amgen, Inc. for this trial. RG has served on the scientific advisory board for Amgen, Inc. for this trial. RH has served as a primary investigator for Amgen, Inc. and Novartis and has served as a board member of the nonprofit Mattie Miracle Cancer Foundation. HG’s institution has received grants and consultancy fees from Amgen, Inc. EC has served as a consultant on advisory boards for Amgen, Inc., EMD Serono, and Bayer. SC has served as an advisor and consultant for Amgen, Inc. PR has served on advisory boards for Novartis; Pfizer; Bayer; PharmaMar; Ariad; Amgen, Inc.; GlaxoSmithKline; AstraZeneca; Clinigen; and Lilly and has received honoraria from Novartis; Pfizer; Bayer; PharmaMar; Amgen, Inc.; GlaxoSmithKline; and Lilly. MO is an employee of CoreLab Partners (now Bioclinica). AF, IJ, ZJR, AB, and BAB were employees of Amgen, Inc. at the time of the study; they are currently employees of Atara Biotherapeutics, Inc.; Pfizer; Kite Pharma, Inc.; Arog Pharmaceuticals, Inc.; and AbbVie, respectively.
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