Funding for this research was provided by:
National Natural Science Foundation of China (81300468, 81671433)
Science and Technology Development Program of Jinan (201506012)
Shandong Province key research and development projects (2016GSF201086)
Shandong Province medical and health technology development project (2016WS0442)
Natural Science Foundation of Shandong Province (CN) (No. ZR2014HM008)
Received: 26 December 2017
Accepted: 4 June 2018
First Online: 23 June 2018
Ethics approval and consent to participate
: Informed consent was obtained from all participants prior to biopsy and the use of human tissues was approved by the Institutional Research Ethics Committees of Shandong Provincial Hospital Affiliated to Shandong University. Written informed consent was obtained from all participants before being included in the study.
: The authors declare that they have no competing interests.
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