Received: 13 March 2020
Accepted: 12 May 2020
First Online: 19 May 2020
Ethics approval and consent to participate
: The study was conducted at “Santa Maria alle Scotte” University Hospital, Department of Molecular and Developmental Medicine and all experiments were performed in strict accordance with the local Ethics Committee. Informed consent was obtained from all subjects. The study was approved by the ethical committee of the Siena University under the ID 10818_2017 clinical protocol.
: All co-authors have seen and approved the final version of the paper and have agreed to its submission for publication. All patients signed informed written consent forms.
: The authors declare that they have no competing interests.