Funding for this research was provided by:
Medical Research Council (Grant MC_UU_00006/6)
National Institute for Health Research (RP-PG-0216-20010)
National Prevention Research Initiative (MR/J000493)
Received: 27 May 2021
Accepted: 20 October 2021
First Online: 7 November 2021
: Ethical approval for up to 2 year post randomisation assessment was received by East of England Cambridge East and local approvals from NRES Committee North West Liverpool Central and NRES Committee South Central Oxford. Ethical approval for 5 years post randomisation assessment was received from West Midlands- Coventry and Warwickshire Research Ethics Committee 8th December 2017. The original trial (ISRCTN82857232) and 5 year follow up (ISRCTN64986150) were prospectively registered with Current Controlled Trials on 15/10/2012 and 01/02/2018 (ExternalRef removed; ExternalRef removed).
: At enrolment, a member of the research team trained in taking informed consent ensured participants understood the trial and had read the participant information sheet. All participants provided written informed consent for their participation in the trial.
: RAJ, JM, RD and SS declare that they have no competing interests. ALA and SJG are the principal investigators on two publicly funded (MRC, NIHR) trials where the intervention is provided by WW (formerly Weight Watchers) at no cost outside the submitted work.