Funding for this research was provided by:
National Natural Science Foundation of China (31471057, 81271324, 31671080)
foundation from the Major State Research Development Program of Liaoning, China (2017225024)
foundation from the Project for Construction of Major Discipline Platform in Universities of Liaoning province, China (2017001)
foundation from Clinical Medical Research Center of Shenyang, Liaoning, China (18_009-4-03)
Received: 24 March 2019
Accepted: 10 December 2019
First Online: 21 December 2019
Ethics approval and consent to participate
: The studies have been approved by the ethics committee of the first affiliated hospital of China Medical University. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
: Not applicable.
: The authors declare that they have no competing interests.