Funding for this research was provided by:
2017 Shandong Province Medical and Health Development Plan (2017ws302)
Received: 16 January 2019
Accepted: 20 May 2019
First Online: 6 June 2019
Ethics approval and consent to participate
: The experiment protocol was approved by the Ethics Committee and Institutional Animal Care and Use Committee of Qilu Hospital of Shandong University (Qingdao Hospital District). Signed informed consents were obtained from all participants and the experiments were conducted in line with the ethical principles of Declaration of Helsinki. All animal experimentation was carried out in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health.
: Not applicable.
: The authors declare that they have no competing interests.