Funding for this research was provided by:
the Research Special Fund for Public Welfare Industry of Health (201402008)
the National High Technology Research and Development Program of China (2014AA020610)
National Natural Science Foundation of China (81702455)
Received: 29 April 2019
Accepted: 18 August 2019
First Online: 28 August 2019
Ethics approval and consent to participate
: This study was approved by the Ethics Committee of Beijing Tiantan Hospital (KY2013-015-02). And the study was performed in compliance with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.Written informed consent was obtained from all of the enrolled subjects.
: All authors approved the submission.
: We certify this manuscript has not been published in whole or in part nor is it being considered for publication elsewhere. The authors declare that they have no competing interests.