Funding for this research was provided by:
Instituto de Salud Carlos III (FI19-00091, PI18-00612, PI15-01648)
Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía (CTS-1664)
Consejería de Salud, Junta de Andalucía (PEER-0501-2019)
Centro de Investigación Biomédica en Red de Enfermedades Raras (ER16P1AC702/2017)
Fundación Isabel Gemio / Fundación Cajasol
Text and Data Mining valid from 2020-02-12
Received: 27 September 2019
Accepted: 5 February 2020
First Online: 12 February 2020
Ethics approval and consent to participate
: This study was conducted according to the ethical principles for medical research involving human subjects according to the Declaration of Helsinki (Edinburgh, 2000). Prior to the study, written informed consents were obtained from all participants or their legal guardians for clinical and molecular genetic studies, which was approved by the Ethical Committees of the University Hospital Virgen del Rocio (Seville) and the University Hospital Virgen Macarena (Seville).
: Consent for publication was obtained from the affected subjects of family in study.
: The authors declare that they have no competing interests.