Funding for this research was provided by:
National Science Foundation (1746694)
Brain Aneurysm Foundation
NYS CAT in Big Data and Health Sciences
Received: 9 March 2020
Accepted: 27 September 2020
First Online: 15 October 2020
Ethics approval and consent to participate
: This study was approved by the University at Buffalo Health Sciences Institutional Review Board (study no. 030–474433). All methods were carried out in accordance with approved protocol and informed consent was obtained from all subjects.
: No specific patient information or images are given in the manuscript.
: KEP, LL, MW, AJ, LC, KJ, YS, JK—None. VMT— Principal investigator: National Science Foundation Award No. 1746694, and the Brain Aneurysm Foundation grant, Center for Advanced Technology grant, and Cummings Foundation grant mentioned above. Co-founder: Neurovascular Diagnostics, Inc. JNJ—Principal Investigator: NIH Grant R01-AR-060604. KVS—Consulting and teaching for Canon Medical Systems Corporation, Penumbra Inc., Medtronic, and Jacobs Institute. Co-Founder: Neurovascular Diagnostics, Inc. EIL—Intratech Medical Ltd., NeXtGen Biologics. Principal investigator: Medtronic US SWIFT PRIME Trials. Honoraria–Medtronic. Consultant–Pulsar Vascular. Advisory Board-Stryker, NeXtGen Biologics, MEDX. Cognition Medical. Other financial support—Abbott Vascular for carotid training sessions. AHS—Financial Interest/Investor/Stock Options/Ownership: Amnis Therapeutics, Apama Medi- cal, BlinkTBI, Inc, Buffalo Technology Partners, Inc., Cardinal Health, Cerebrotech Medical Systems, Inc, Claret Medical, Cognition Medical, Endostream Medical, Ltd, Imperative Care, International Medical Distribution Partners, Rebound Therapeutics Corp., Silk Road Medical, StimMed, Synchron, Three Rivers Medi- cal, Inc., Viseon Spine, Inc. Consultant/Advisory Board: Amnis Therapeutics, Boston Scientific, Canon Medical Systems USA, Inc., Cerebrotech Medical Systems, Inc., Cerenovus, Claret Medical, Corindus, Inc., Endostream Medical, Ltd, Guidepoint Global Consulting, Imperative Care, Integra, Medtronic, Micro- Vention, Northwest University—DSMB Chair for HEAT Trial, Penumbra, Rapid Medical, Rebound Therapeutics Corp., Silk Road Medical, StimMed, Stryker, Three Rivers Medical, Inc., VasSol, W.L. Gore & Associates. National PI/Steering Committees: Cerenovus LARGE Trial and ARISE II Trial, Medtronic SWIFT PRIME and SWIFT DIRECT Trials, MicroVention FRED Trial & CONFIDENCE Study, MUSC POSITIVE Trial, Penumbra 3D Separator Trial, COMPASS Trial, INVEST Trial. HM— Principal investigator: NIH Grants R01-NS-091075 and R01-NS-064592. Grant support: Canon Medical Systems. Co-founder: Neurovascular Diagnostics, Inc.