Funding for this research was provided by:
China Postdoctoral Science Foundation (No. 2020TQ0394)
National Natural Science Foundation of China (No. 82173303)
Natural Science Foundation of Chongqing (No. cstc2020jcyj-msxmX1089)
Received: 12 February 2022
Accepted: 30 May 2022
First Online: 6 June 2022
: Clinical specimens were acquired from patients undergoing hypopharyngectomy in the First Affiliated Hospital of Chongqing Medical University. Informed consent was obtained from each patient, and all protocols concerning the use of clinical specimens in this study were approved by the Ethics Committee of the First Affiliated Hospital of Chongqing Medical University. All experiments were performed in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki). Meanwhile, all in vivo experiments on mice were approved by the Ethics Committee of the First Affiliated Hospital of Chongqing Medical University and performed in accordance with the U.K. Animals (Scientific Procedures) Act and the guidelines of the National Institutes of Health.
: We have obtained consents to publish this paper from all the participants of this study.
: The authors declare that they have no competing interests.