Funding for this research was provided by:
National Institutes of Health (R01HL113352, R01HL122560)
Received: 5 May 2017
Accepted: 17 July 2017
First Online: 18 August 2017
Ethics approval and consent to participate
: Animal studies were performed in accordance with Yale School of Medicine Animal Care and Use Committee (IACUC). All animals received humane care in compliance with the “Guide for the Care and Use of Laboratory Animals” published by the National Institutes of Health, the Animal Welfare Act, and Animal Welfare Regulations.The patient study was approved by Yale School of Medicine Review Board (IRB) and all patients provided informed written consent.
: We confirm that a written informed consent for publication was obtained from every patient involved in the study.
: The authors declare that they have no competing interests.