Funding for this research was provided by:
National Institute on Aging (AG043540)
National Institute on Drug Abuse (DA028555)
National Institute of Neurological Disorders and Stroke (NS036126, NS034239, NS043985)
National Institute of Mental Health (MH064570, MH062261)
Defense Advanced Research Projects Agency (421-20-09A)
Carol Swarts Emerging Neuroscience Fund
Shoemaker Award for Neurodegenerative Research
Received: 22 November 2017
Accepted: 23 April 2018
First Online: 5 May 2018
: Housing, care, and breeding of non-Tg and APP/PS1 double-Tg mice were approved by the Institutional Animal Care and Use Committee at the University of Nebraska Medical Center.
: The authors with the exception of HAG and HEG declare that they have no competing interests. HAG and HEG hold patents applicable to URMC-099.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.