Funding for this research was provided by:
National Institute on Aging (U01 AG052460)
National Institute of Neurological Disorders and Stroke (R33 NS10167)
Received: 2 June 2021
Accepted: 14 October 2021
First Online: 20 November 2021
: All experimental procedures involving animals were conducted according to the “Principles of laboratory animal care” (NIH publication No. 86-23, revised 1985), and were approved by the Emory University School of Medicine’s Animal Care and Use Committee and justified to the NIH guidelines for animal research. Histological and gene expression studies were carried out in a blinded manner by the use of animal and sample codes. The identity of the samples and animals were only revealed at the time of data analysis.
: All authors agree to the publication of this manuscript.
: Authors T.G. and R.D. are the founder of, and have equity in Pyrefin Inc, which has licensed EP2 technology from Emory University in which T.G., R.D. and R.A. are inventors.