Funding for this research was provided by:
Capital Health Research and Development of Special (2020-2Z-20411)
National Key R&D Program of China (2016YFC0901002, 2017YFC1310901, 2018YFC1312903)
National Natural Science Foundation of China (81970425, 81770272)
China National Key R&D Program (2020YFA0803700)
Beijing Municipal Science & Technology Commission (D171100003017002)
National Science and Technology Major Project (2017ZX09304018)
China Postdoctoral Science Foundation (2021M692248)
Beijing Postdoctoral Research Foundation (2021-ZZ-020)
Received: 27 September 2021
Accepted: 15 December 2021
First Online: 28 December 2021
: According to the principles mentioned in the Declaration of Helsinki, the ethics committees of Beijing Tiantan Hospital and all other recruited participating centers approved the study protocol. Written informed consent was obtained from all participants (or guardians of participants) in this study.
: All authors have approved this manuscript.
: The authors declare that they have no competing interests.