Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (FOR 1232, KA 1546/6-1, KA 1546/7-1)
Text and Data Mining valid from 2018-04-16
Received: 12 December 2017
Accepted: 29 March 2018
First Online: 16 April 2018
Ethics approval and consent to participate
: All experiments were conducted in accordance with the institution’s animal care and use guidelines and approved by the national and local authorities (LANUV-NRW; reference number: 84-02.05.20.12.211). All procedures complied with the regulations covering animal experimentation within the EU (European Communities Council DIRECTIVE 2010/63/EU).
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.