Received: 22 April 2020
Accepted: 12 October 2020
First Online: 4 January 2021
Ethics approval and consent to participate
: Both studies were carried out in accordance with the recommendations of the Oregon Health & Science University (OHSU) institutional review board (IRB) with written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki. The protocols were approved by the OHSU IRB (#9903, #10775 and #15578).
: Not applicable.
: Dr. Horak have a significant financial interest in APDM, a company that may have a commercial interest in the results of this research and technology. Dr. Horak also consults for Biogen, Neuropore, Sanofi, and Takeda. This potential individual conflict has been reviewed and managed by OHSU.