Funding for this research was provided by:
National Natural Science Foundation of China (81471937)
Regional Science Fund of National Natural Science Foundation of China (81760379)
the Yangcheng Scholars Research Fund for Guangzhou Municipal Universities (1201561571)
Foundation for Medical Discipline Leader in Health and Family Planning Commission of Yunnan Province (D-2017050)
Text and Data Mining valid from 2019-06-07
Received: 26 December 2018
Accepted: 30 April 2019
First Online: 7 June 2019
Ethics approval and consent to participate
: All animal research was approved by the Guangdong Provincial Department of Science and Technology, which complied with the guidelines of Guangdong Regulation for Administration of Laboratory Animals (2010), and the guidelines on the welfare of medical experiment animal were used in research. Animals were allowed free access to food and water and kept on a 12-h light/dark cycle, received environmental enrichment and were monitored daily for evidence of disease and changes in attitude, appetite, or behavior suggestive of illness. In cases of suffering animals were treated with anesthetic or otherwise the experiment was stopped by humane killing (excessive injection of pentobarbital sodium) with subsequent post mortem analysis.
: Not applicable.
: The authors declare that they have no competing interests.
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