Received: 26 November 2020
Accepted: 27 May 2021
First Online: 3 June 2021
: All work described has been carried out in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki) for experiments involving humans. All animal experiments are carried out in accordance with the U.K. Animals (Scientific Procedures) Act, 1986 and associated guidelines.
: No applicable.
: The authors declare that they have no competing interests.