Funding for this research was provided by:
Wellcome Trust (080268)
Biotechnology and Biological Sciences Research Council (BB/L01534X/1)
UCLH Biomedical Research Centre
Medical Research Council (MR/K500811/1)
Medical Research Council DTP (MR/N013700/1)
KCL ARUK network fund
GSTT MRes-PhD Studentship
The Edmond and Lily Safra Research Foundation
Text and Data Mining valid from 2019-12-01
Received: 10 October 2019
Accepted: 2 December 2019
First Online: 17 December 2019
Ethics approval and consent to participate
: Human tissue was provided with informed consent via the brains for dementia research (BDR) and were anonymized. BDR has ethical approval granted by the national health service (NHS) health research authority (NRES Committee London-City & East, UK: REC reference:08/H0704/128+5. IRAS project ID:120436). Tissue was received on the basis that it will be handled, stored, used and disposed of within the terms of the Human Tissue Act 2004. Specifically the human brain tissue samples were supplied by The Manchester Brain Bank, which is part of the Brains for Dementia Research programme jointly funded by Alzheimer’s Research UK and Alzheimer’s Society (BDR Reference: Amendment to study-BDR14 TRID 170 recipient PI: Dr. Sarah Thomas).
: Not applicable.
: The authors declare that they have no competing interests.