Received: 19 June 2019
Accepted: 6 December 2019
First Online: 24 February 2020
Ethics approval and consent to participate
: The protocols of this study were approved by the Ethics Committee of Peking University First Hospital University. All the participants provided the written informed consents.The protocols for animal experiments were approval by the Animal Ethics Committee of Peking University.
: Written informed consent for publication was obtained from each participant.
: The authors declare that they have no competing interests.