Funding for this research was provided by:
National Basic Research Program of China (973 Program) (2016YFC0900500,2016YFC0900501,2016YFC0900504)
Ministry of Science and Technology of the People's Republic of China (2011BAI09B01)
National Natural Science Foundation of China (81202266)
Wellcome Trust (104085/Z/14/Z)
Kadoorie Charitable Foundation in Hong Kong (088158/Z/09/Z)
Text and Data Mining valid from 2019-05-09
Received: 4 October 2018
Accepted: 26 April 2019
First Online: 9 May 2019
Ethics approval and consent to participate
: National and international ethical approval was obtained from the Ethical Review Committee of the Chinese Centre for Disease Control and the Institutional Review Boards at Oxford University. All study participants provided written informed consent.
: Not applicable.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.