Received: 15 September 2017
Accepted: 8 January 2018
First Online: 26 January 2018
Ethics approval and consent to participate
: This study adheres to the principles of the Helsinki Declaration and was carried out through routine diagnostic activity; formal ethics review was therefore not requested by our institutional ethical committee for the targeted next generation sequencing. Couples undergoing further analysis gave their written informed consent for participation in the study.
: All couples provided written informed consent for genetic testing and publication of clinical and genetic data according to the German bioethics laws.
: The authors declare that they have no competing interests.
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